Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Perineural optic nerve changes in endocrine orbitopathy.

H W Skalka

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |March 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Imaging techniques in optic nerve evulsion.

    Journal of clinical neuro-ophthalmology·1988
    Same author

    Electrical cataracts: a case report and review of the literature.

    Ophthalmic surgery·1987
    Same author

    Effects of ethyl alcohol on VECP.

    Documenta ophthalmologica. Advances in ophthalmology·1986
    Same author

    Gas chromatographic analysis of lens monosaccharides.

    The Journal of laboratory and clinical medicine·1984
    Same author

    Update on cataract surgery and intraocular lenses.

    The Alabama journal of medical sciences·1983
    Same author

    Choroidal hemorrhage simulating malignant melanoma.

    Journal of clinical ultrasound : JCU·1982

    Endocrine orbitopathy causes enlargement of the retrobulbar optic nerve and increased intervaginal distension, even without functional optic nerve compromise. The exact cause of this nerve sheath enlargement is still unknown.

    Area of Science:

    • Ophthalmology
    • Endocrinology
    • Medical Imaging

    Background:

    • Endocrine orbitopathy is an autoimmune condition affecting the eye socket.
    • Optic nerve involvement can lead to vision loss in endocrine orbitopathy.
    • Ultrasonography is a valuable tool for assessing orbital structures.

    Purpose of the Study:

    • To investigate ultrasonographic changes in the retrobulbar optic nerve and extraocular muscles in patients with endocrine orbitopathy.
    • To correlate these ultrasonographic findings with the clinical status of thyroid function and extraocular muscle involvement.

    Main Methods:

    • A-scan ultrasonography was used to measure the diameters of the retrobulbar optic nerve and its dural sheath.
    • Extraocular muscle thickness was also measured using ultrasonography.

    Related Experiment Videos

  • Measurements were taken in 55 eyes from 30 patients with varying degrees of endocrine orbitopathy.

    • Main Results:

    • Enlargement of the retrobulbar optic nerve diameter was observed in all evaluated eyes.
    • A positive correlation was found between extraocular muscle involvement and the degree of intervaginal distension.
    • These ultrasonographic findings were consistent across hyperthyroid, hypothyroid, and euthyroid patients.

    Conclusions:

    • Ultrasonography reveals characteristic changes in the retrobulbar optic nerve and extraocular muscles in endocrine orbitopathy.
    • These changes, including nerve sheath enlargement, occur independently of thyroid status and functional optic nerve compromise.
    • The underlying cause of the observed subdural perineural enlargement requires further investigation.