Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Gel model for measuring crystallization inhibitor activity].

C Bothor, W Berg, R H Börner

    Zeitschrift Fur Urologie Und Nephrologie
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Previable preterm premature rupture of membranes: 117 cases with neonatal outcomes in light of current research.

    Journal of neonatal-perinatal medicine·2023
    Same author

    Diagnostics and therapy of bilateral choanal atresia in association with CHARGE syndrome.

    Journal of neonatal-perinatal medicine·2020
    Same author

    [Update of the 2Sk guidelines on the diagnostics, treatment and metaphylaxis of urolithiasis (AWMF register number 043-025) : What is new?]

    Der Urologe. Ausg. A·2019
    Same author

    [Progressive hoarseness-surgical treatment of a benign tumor].

    HNO·2019
    Same author

    [Modern nephrolithiasis in the complex setting of metaphylaxis : Latest epidemiological data and a nationwide survey in private practices].

    Der Urologe. Ausg. A·2019
    Same author

    Externalized Percutaneous Stent Versus Internal Double J Stent: Short- and Long-term Complications After Kidney Transplantation.

    Transplantation proceedings·2018
    Same journal

    [Comment on the contribution "Loss of bone substance in long-term dialysis--value of serochemical parameters"].

    Zeitschrift fur Urologie und Nephrologie·1990
    Same journal

    [Laboratory diagnosis of cystinuria].

    Zeitschrift fur Urologie und Nephrologie·1990
    Same journal

    [Endoscopic removal of urinary calculi in children].

    Zeitschrift fur Urologie und Nephrologie·1990
    Same journal

    [ESWL with the Lithostar--experience with 3,000 treatments].

    Zeitschrift fur Urologie und Nephrologie·1990
    Same journal

    [Obstructive disorders of urine transport of the upper urinary tract--benign and malignant retroperitoneal fibrosis].

    Zeitschrift fur Urologie und Nephrologie·1990
    Same journal

    [Histologic changes after laser treatment of superficial penis tumors].

    Zeitschrift fur Urologie und Nephrologie·1990
    See all related articles

    A simple gel diffusion assay was developed to measure crystallisation inhibitor activity. This method effectively quantifies the inhibitory effects of substances like magnesium and citrate on calcium oxalate crystal formation.

    Area of Science:

    • Biochemistry
    • Materials Science

    Context:

    • Calcium oxalate crystal formation is implicated in kidney stone disease.
    • Accurate measurement of crystallisation inhibitors is crucial for understanding stone formation and developing treatments.

    Purpose:

    • To develop a simple, time-efficient, and material-sparing method for measuring crystallisation inhibitor activity.
    • To establish a reliable assay for quantifying the inhibitory effects on calcium oxalate crystal formation.

    Summary:

    • A novel gel diffusion assay involves diffusing calcium and oxalate ions against each other, forming a calcium oxalate crystal strip.
    • Substances are introduced to the central area, and their inhibitory effects are measured by photometric analysis of the crystal strip's density and extent.
    • An inhibition index is computed by comparing results to a control, with known inhibitors demonstrating defined effects.

    Related Experiment Videos

    Impact:

    • This assay provides a valuable tool for studying crystallisation inhibitors, including those found in physiological fluids like human urine.
    • The method's simplicity and efficiency make it suitable for routine laboratory use and screening potential therapeutic agents.
    • Findings highlight the importance of magnesium and citrate as significant inhibitors at physiological concentrations.