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Virus-associated colitis in homosexual men: two case reports.

D Guttman, A Raymond, A Gelb

    The American Journal of Gastroenterology
    |March 1, 1983
    PubMed
    Summary

    Viral colon infections were identified in two homosexual men with colitis. One case involved toxic megacolon, while the other led to fatal opportunistic infections, highlighting the need for viral testing in this population.

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    Area of Science:

    • Gastroenterology
    • Virology
    • Infectious Diseases

    Background:

    • Colitis and proctitis are inflammatory conditions affecting the lower gastrointestinal tract.
    • Homosexual men represent a demographic that may be at increased risk for certain infections.
    • Viral infections can manifest with gastrointestinal symptoms, including colitis.

    Observation:

    • Two homosexual men presented with symptoms of colitis.
    • Both patients exhibited evidence of viral infection within the colon.
    • One patient experienced toxic megacolon, which was managed conservatively.

    Findings:

    • The second patient developed proctosigmoiditis and subsequent opportunistic infections.
    • This patient's condition progressed, ultimately resulting in mortality.

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  • Viral etiology was confirmed in both cases of colitis.
  • Implications:

    • These cases suggest a potential link between viral infections and colitis in homosexual men.
    • Routine and intensive viral investigation is recommended for homosexual men presenting with proctitis or colitis.
    • Early diagnosis and management of viral colon infections may improve patient outcomes.