Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Orchestration of tooth movement.

Y A Mostafa, M Weaks-Dybvig, P Osdoby

American Journal of Orthodontics

|March 1, 1983

Summary

Orthodontic forces precisely control tooth movement, but the exact tissue reaction mechanism remains unclear. Understanding cellular responses like piezoelectricity and prostaglandins can optimize tooth movement rates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of platelet-rich plasma on orthodontic tooth movement in dogs.

Orthodontics & craniofacial research·2017

Same author

Zygomatic mini-implant for Class II correction in growing patients.

Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie·2014

Same author

Personal factors and working conditions as predictors of work injuries among industrial workers.

The Journal of the Egyptian Public Health Association·2007

Same author

Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis.

The Journal of biological chemistry·2001

Same author

Isolation, screening and characterization of bacteriocin-producing lactic acid bacteria isolated from traditional fermented food.

Microbiological research·2000

Same author

Decreased nitric oxide levels stimulate osteoclastogenesis and bone resorption both in vitro and in vivo on the chick chorioallantoic membrane in association with neoangiogenesis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2000

Area of Science:

Biomedical Engineering
Orthodontics
Cell Biology

Background:

Orthodontic treatment relies on controlled application of forces for precise tooth movement.
The precise biological mechanisms underlying orthodontic tooth movement are not fully elucidated.
Optimizing treatment efficiency requires a deeper understanding of cellular responses to orthodontic forces.

Purpose of the Study:

To present an integrated hypothetical model for orthodontic tooth movement.
To explain how various stimuli influence bone cells during orthodontic treatment.
To emphasize the role of specific biological factors in maximizing tooth movement velocity.

Main Methods:

Review and synthesis of recent scientific literature on cellular responses to mechanical stimuli.
Discussion of the roles of piezoelectric responses, prostaglandin production, and biochemical factors.
Development of a hypothetical model integrating current knowledge of bone cell biology and orthodontic mechanics.

Main Results:

The model highlights the interplay between mechanical forces and cellular signaling pathways.
Piezoelectric effects, prostaglandin synthesis, and other biochemical factors are identified as key mediators of bone remodeling.
These factors significantly influence the rate and efficiency of orthodontic tooth movement.

Conclusions:

A comprehensive understanding of the cellular mechanisms governing tooth movement is crucial for treatment optimization.
The proposed model provides a framework for understanding how to enhance orthodontic appliance and treatment regimens.
Intelligent application of this knowledge can lead to improved patient outcomes and reduced treatment times.

Related Experiment Videos