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Herpes simplex encephalitis treated with adenine arabinoside.
Brain & Development
|January 1, 1982
Summary
Adenine arabinoside (ara-A) effectively treated herpes simplex encephalitis (HSE) in a young patient. Early intervention with ara-A led to recovery with only mild motor aphasia, suggesting its therapeutic potential.
Area of Science:
- Pediatric Neurology
- Virology
- Infectious Diseases
Background:
- Herpes simplex encephalitis (HSE) is a severe neurological condition.
- Prompt diagnosis and treatment are crucial for patient outcomes.
Observation:
- A 5-year-old girl presented with HSE symptoms including headache, vomiting, and altered consciousness.
- A CT scan showed a lesion in the left temporal lobe.
Findings:
- Treatment with adenine arabinoside (ara-A) was initiated seven days after symptom onset.
- The patient recovered with minimal sequelae, experiencing only mild motor aphasia.
Implications:
- Early administration of ara-A may be effective in treating HSE.
- This case highlights the potential of antiviral therapy in managing pediatric HSE.