Related Experiment Video
Updated: Aug 2, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
[Thyroid hormones in alcoholic cirrhosis before and after alcohol withdrawal]
Abstract:
In a controlled study, the authors have assayed the serum values of thyroid hormones, TSH, reverse T3 (rT3) and the T4/TBG ratio in patients with alcoholic liver cirrhosis before and after 15 days of total abstinence from alcohol. Before abstinence, they show a significant decrease of T3 and a significant increase of r T3. Only T3 values are correlated to the clinical and biological signs of liver cirrhosis. The T3 and rT3/T3 ratio allow a good evaluation of the severity of the cirrhotic condition. The study, after abstinence from alcohol, shows an improvement of both biological abnormalities and T3, rT3, rT3/T3 values. Pathogenic mechanisms of these disturbances are discussed and therapeutic prospects considered.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
CNS Depressants: Alcohol and Nicotine
Hyperthyroidism I: Introduction
Hyperthyroidism II: Pathophysiology
Graves Disease II: Pathophysiology
Cirrhosis I: Introduction

