Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Age-related changes in pituitary/thyroid function in chickens.

B L Carr, R B Chiasson

    General and Comparative Endocrinology
    |April 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Factors that influence the observed fast fragmentation of peptides in matrix-assisted laser desorption.

    Journal of the American Society for Mass Spectrometry·2013
    Same author

    Pseudomonas-induced bilateral endophthalmitis with corneal perforation in a neonate.

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·1999
    Same author

    Immunocytochemical demonstration of chicken hypophyseal thyrotropes and development of a radioimmunological indicator for chicken TSH using monoclonal and polyclonal homologous antibodies in a subtractive strategy.

    General and comparative endocrinology·1993
    Same author

    Autoradiography of pituitary cells stimulated by castration or methimazole feeding.

    Acta biologica Hungarica·1993
    Same author

    Role of ovarian steroids in the control of moult induction in laying fowls.

    British poultry science·1988
    Same author

    Effect of exogenous LH on plasma concentrations of progesterone and oestradiol in relation to the cessation of egg laying induced by different moulting methods.

    Journal of reproduction and fertility·1987
    Same journal

    Modulatory effect of probiotics and Spirulina platensis on the growth performance and immune response of Nile tilapia exposed to sumithion.

    General and comparative endocrinology·2026
    Same journal

    Nonapeptide modulation of looming-induced responses in male Betta splendens.

    General and comparative endocrinology·2026
    Same journal

    Phytochemicals as eco-friendly modulators of ovarian vitellogenesis and reproductive efficiency in aquaculture.

    General and comparative endocrinology·2026
    Same journal

    Roles of the FAM237-derived small proteins in energy homeostasis: a comparative perspective of neurosecretory protein GL and GM across vertebrates.

    General and comparative endocrinology·2026
    Same journal

    Nucleobindin-derived peptides and stress regulation in vertebrates.

    General and comparative endocrinology·2026
    Same journal

    Circulating testosterone is not associated with social challenge or aggression in female northern house wrens (Troglodytes aedon).

    General and comparative endocrinology·2026
    See all related articles

    Older chickens show reduced pituitary response to thyrotropin-releasing hormone (TRH), potentially due to hypothalamic or thyroid issues. However, their thyroids exhibit higher basal activity, with females showing some TRH response.

    Area of Science:

    • Endocrinology
    • Gerontology
    • Comparative Physiology

    Background:

    • Aging affects hormonal regulation in chickens.
    • Thyrotropin-releasing hormone (TRH) is crucial for thyroid function.
    • Cyclic AMP-dependent protein kinase (cAMP-PK) activity is a key indicator of cellular response to hormones.

    Purpose of the Study:

    • To investigate the effect of aging on the pituitary and thyroid response to TRH in chickens.
    • To determine if age-related changes in cAMP-PK activity ratios are sex-specific.
    • To explore potential mechanisms behind reduced TRH responsiveness in older chickens.

    Main Methods:

    • Measurement of pituitary and thyroid cAMP-PK activity ratios in young and old male and female chickens.
    • Administration of TRH and subsequent assessment of cAMP-PK activity.

    Related Experiment Videos

  • Comparison of basal and TRH-stimulated activity ratios between age groups and sexes.

    • Main Results:

    • Old chickens did not show increased pituitary cAMP-PK activity in response to TRH.
    • Thyroid cAMP-PK activity ratios in old males did not respond to TRH, while old females showed an increase.
    • Both old male and female chickens exhibited higher basal cAMP-PK activity ratios compared to young birds.

    Conclusions:

    • Aging in chickens leads to diminished pituitary responsiveness to TRH.
    • Sex-specific differences exist in the thyroid response to TRH in aged chickens.
    • Elevated basal cAMP-PK activity in old chickens may result from increased thyroid-stimulating hormone (TSH) stimulation, and impaired TRH response in males suggests a loss of direct thyroid sensitivity.