[Drug metabolism: chronic alcoholism and cirrhosis]

The growing interest for research addressing the interactions between drug and alcohol metabolisms is not unrelated to the increasing prevalence of alcoholism and associated drug additions. Most physicians are now aware of the increased therapeutic risk in alcoholics, but the intimate mechanism of this interaction is usually unknown. On the whole, while many studies address the problems related to drug-alcohol interactions, those on the interactions between chronic alcoholism and cirrhosis are scarce or imprecise.