Fibrolamellar carcinoma: distinctive clinical and morphologic variant of hepatoma

We present two cases of fibrolamellar carcinoma. Because of its usual presentation as a solitary mass in the noncirrhotic liver of a young girl, this tumor is likely to be mistaken clinically for a benign lesion. Its microscopic appearance is unique and easily separated from other types of hepatocellular carcinoma, an important distinction because of the better prognosis of fibrolamellar carcinoma.