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Updated: Oct 13, 2026

08:53
Competitive Transplants to Evaluate Hematopoietic Stem Cell Fitness
Published on: August 31, 2016
[Factors controlling stem cell recirculation. 5. Modification of the effects of endogenous glucocorticoids on CFUs
Abstract:
It was shown that at a continuously increased level of endogenous glucocorticoids (injection of ACTH) in thymectomized and B mice the degree of inhibition of CFUs migration, that was observed in T-deficient mice without ACTH injection, did not increase. With T-deficiency the stimulatory effect of the hypocorticoid state (adrenalectomy) on the CFUs migration persisted but was less pronounced than in animals with intact thymus.

