Related Experiment Video
Updated: Jul 17, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Ultrastructural study of corpora amylacea in human thyroid gland
Abstract:
Large cytoplasmic inclusions, corpora amylacea, were found in the follicle epithelial cells of a thyroid with medullary carcinoma. They were varied in size from 1.5 to 10 microns in dimension and the shapes were from fusiform to irregularly formed. Fine fibrils 8 to 23 nm in diameter were randomly arranged within the inclusions. The findings from our work and experience of others suggest that the inclusion bodies may be nonspecific or that an accumulation of abnormal cellular inclusions could be caused by various illness.
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Hyperthyroidism II: Pathophysiology
Graves Disease II: Pathophysiology
Goiter

