Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Factors affecting plasma benzo[a]pyrene levels in environmental studies.

D E Hutcheon, J Kantrowitz, R N Van Gelder

    Environmental Research
    |October 1, 1983
    PubMed
    Summary

    Plasma benzo[a]pyrene (BaP) levels were higher in urban-industrial areas. Radioimmunoassay can assess polycyclic aromatic hydrocarbon (PAH) exposure, but obesity influences results.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pregnancy outcomes of Ukrainian displaced women in Dublin.

    Irish medical journal·2024
    Same author

    Prevalence of hepatitis C virus exposure and infection among Indigenous and tribal populations: a global systematic review and meta-analysis.

    Public health·2024
    Same author

    Early lacunar changes in congenital hypertrophy of the retinal pigment epithelium in an eighteen-year-old.

    Journal francais d'ophtalmologie·2023
    Same author

    Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run.

    Physical review letters·2021
    Same author

    Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.

    Living reviews in relativity·2020
    Same author

    GW190521: A Binary Black Hole Merger with a Total Mass of 150  M_{⊙}.

    Physical review letters·2020

    Area of Science:

    • Environmental Health
    • Toxicology
    • Biomarkers

    Background:

    • Polycyclic aromatic hydrocarbons (PAHs) are airborne carcinogens.
    • Benzo[a]pyrene (BaP) serves as a key indicator of PAH exposure.
    • Assessing environmental exposure requires reliable measurement methods.

    Purpose of the Study:

    • To investigate plasma BaP level differences across distinct geographic-demographic locales.
    • To evaluate the utility of radioimmunoassay for measuring BaP as a biomarker of PAH exposure.
    • To explore the influence of physiological factors, such as obesity, on plasma BaP levels.

    Main Methods:

    • Radioimmunoassay (RIA) was employed to quantify plasma BaP concentrations.
    • Sixty-one subjects were categorized into three groups: urban-industrial, urban-residential, and outer suburban.

    Related Experiment Videos

  • Quetelet's index was used to assess obesity.

    • Main Results:

    • Participants from urban-industrial areas exhibited significantly higher mean plasma BaP levels compared to outer suburban subjects.
    • No significant difference in mean plasma BaP was observed between urban-residential subjects and the other two groups.
    • Obesity demonstrated a significant positive correlation with plasma BaP levels.

    Conclusions:

    • Radioimmunoassay of plasma BaP is a viable method for assessing environmental PAH exposure.
    • Geographic location, specifically urban-industrial settings, is associated with elevated BaP levels.
    • Obesity must be considered as a confounding factor when interpreting plasma BaP levels as a measure of PAH exposure.