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[Simultaneous bilateral Wilms' tumors]
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|October 1, 1983
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Bilateral Wilms
Area of Science:
- Pediatric Oncology
- Nephrology
Background:
- Wilms' tumor, a common pediatric kidney cancer, can occur bilaterally in 4-14% of cases.
- Bilateral Wilms' tumors can manifest simultaneously or metachronously, necessitating thorough contralateral kidney examination.
Purpose of the Study:
- To investigate the incidence and diagnosis of simultaneous bilateral Wilms' tumors.
- To evaluate the radiological procedures crucial for diagnosing bilateral Wilms' tumor.
- To compare the prognosis of simultaneous bilateral Wilms' tumors with metachronous and unilateral cases.
Main Methods:
- Retrospective analysis of 52 pediatric patients diagnosed with Wilms' tumor.
- Detailed review of radiological imaging and diagnostic procedures for bilateral cases.
- Comparative analysis of treatment outcomes and survival rates based on tumor occurrence (simultaneous, metachronous, unilateral).
Main Results:
- Simultaneous bilateral Wilms' tumor occurred in 9.6% (5 out of 52) of the studied patients.
- Radiological procedures play a vital role in the accurate diagnosis of bilateral Wilms' tumor.
- The prognosis for simultaneous bilateral Wilms' tumors is significantly better than for metachronous cases and comparable to unilateral Wilms' tumor.
Conclusions:
- Thorough examination of the contralateral kidney is essential in all Wilms' tumor diagnoses.
- Early detection through appropriate radiological methods improves outcomes for bilateral Wilms' tumor.
- Simultaneous bilateral Wilms' tumor carries a favorable prognosis, similar to unilateral disease.
Abstract:
Wilms' tumors occur in 4-14% bilaterally, partially simultaneously, partially metachronously. Therefore in every case with Wilms' tumor the contralateral kidney has to be examined thoroughly too. 5 children of a series of 52 patients with Wilms' tumor showed simultaneous bilateral occurrence (9,6%). The radiological procedures and their importance in diagnosis of bilateral Wilms' tumor are discussed. The prognosis of simultaneous bilateral Wilms' tumors is much better than that of metachronous ones and almost the same as that of unilateral ones.