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[Simultaneous bilateral Wilms' tumors].

F G van den Berg, J H Hendriks, C Boetes

    Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
    |October 1, 1983
    PubMed
    Summary
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    Bilateral Wilms

    Area of Science:

    • Pediatric Oncology
    • Nephrology

    Background:

    • Wilms' tumor, a common pediatric kidney cancer, can occur bilaterally in 4-14% of cases.
    • Bilateral Wilms' tumors can manifest simultaneously or metachronously, necessitating thorough contralateral kidney examination.

    Purpose of the Study:

    • To investigate the incidence and diagnosis of simultaneous bilateral Wilms' tumors.
    • To evaluate the radiological procedures crucial for diagnosing bilateral Wilms' tumor.
    • To compare the prognosis of simultaneous bilateral Wilms' tumors with metachronous and unilateral cases.

    Main Methods:

    • Retrospective analysis of 52 pediatric patients diagnosed with Wilms' tumor.
    • Detailed review of radiological imaging and diagnostic procedures for bilateral cases.
    • Comparative analysis of treatment outcomes and survival rates based on tumor occurrence (simultaneous, metachronous, unilateral).

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    Main Results:

    • Simultaneous bilateral Wilms' tumor occurred in 9.6% (5 out of 52) of the studied patients.
    • Radiological procedures play a vital role in the accurate diagnosis of bilateral Wilms' tumor.
    • The prognosis for simultaneous bilateral Wilms' tumors is significantly better than for metachronous cases and comparable to unilateral Wilms' tumor.

    Conclusions:

    • Thorough examination of the contralateral kidney is essential in all Wilms' tumor diagnoses.
    • Early detection through appropriate radiological methods improves outcomes for bilateral Wilms' tumor.
    • Simultaneous bilateral Wilms' tumor carries a favorable prognosis, similar to unilateral disease.