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Calculation of right and left ventricular ejection fraction in infants and children by first pass radionuclide
Insights
This study found radionuclide angiocardiography a useful, noninvasive method for assessing ventricular ejection fraction in children. It correlated well with contrast angiography for left ventricular function but less so for the right ventricle.
Area of Science:
- Pediatric Cardiology
- Nuclear Cardiology
- Diagnostic Imaging
Background:
- Assessing ventricular function is crucial in pediatric cardiology.
- Traditional methods like contrast angiography can be invasive.
- Noninvasive techniques are needed for accurate cardiac evaluation in children.
Purpose of the Study:
- To evaluate the utility of first-pass radionuclide angiocardiography for determining right and left ventricular ejection fraction in pediatric patients.
- To compare radionuclide angiocardiography measurements with contrast angiography.
- To establish a noninvasive method for assessing cardiac function in infants and children.
Main Methods:
- Seventy-four infants and children underwent first-pass radionuclide angiocardiography.
- Cardiac cycle synchronization used ventricular time activity curve peaks/valleys, not ECG R-waves.
- Results were compared with contrast angiographic measurements.
Main Results:
- Left ventricular ejection fractions from radionuclide angiocardiography showed strong correlation with contrast angiography (r=0.90).
- Right ventricular ejection fractions demonstrated a weaker correlation (r=0.74).
- The radionuclide technique proved useful for evaluating both ventricular ejection fractions.
Conclusions:
- First-pass radionuclide angiocardiography is a valuable noninvasive tool for pediatric ventricular function assessment.
- The method shows good agreement for left ventricular ejection fraction but requires further validation for right ventricular ejection fraction.
- This technique offers a promising alternative to invasive procedures for pediatric cardiac imaging.
Abstract:
First pass radionuclide angiocardiography was utilized to calculate right and left ventricular ejection fraction in 74 infants and children. For the synchronization of radionuclide imaging with the cardiac cycle, the peaks and valleys of corrected ventricular time activity curve were adopted as the time reference points instead of R wave of electrocardiogram. Left ventricular ejection fractions obtained by the radionuclide technique correlated well with those derived from the contrast angiographic technique (r = 0.90), but right ventricular ejection fractions correlated less well (r = 0.74). This noninvasive technique appeared useful for evaluation of right and left ventricular ejection fraction.