[Second tumor in lymphogranulomatosis]

The study was concerned with second malignancies which arose from non-hematopoietic tissue in 6 Hodgkin's disease patients. The malignancies were detected within 15-150 months and appeared to be the immediate cause of the death of the patients. The clinical course of Hodgkin's disease and second malignancy, the terms of second malignancy detection v. previous treatment, morphological features of Hodgkin's disease and the effect of splenectomy are discussed. It is concluded that the rise of second malignancy development should be taken into consideration when procedures for treatment of Hodgkin's disease are selected, particularly, in cases with favorable prognosis.