[Postnatal adaptation of gluconeogenic and liponeogenic areas in the liver parenchyma]

The activity of G6Pase points to the gluco(neo)genic function of hepatocytes, whereas the activity of G6PDH and malic enzyme, both yielding NADPH, are involved in liponeogenesis. Histochemical studies of the distribution patterns and quantitative measurements concerning the postnatal weeks of rats show that after the 6th week sex differences occur. In contrast to males in female rat liver a lipogenic area emerges in the perivenous zone. This lipogenic zone is situated opposite to the gluco(neo)genic area which corresponds to the periportal zone.