Related Experiment Video
Updated: Jul 24, 2026
Fast and Specific Assessment of the Halogenating Peroxidase Activity in Leukocyte-enriched Blood Samples
Published on: July 28, 2016
A comparative kinetics study of monochloramine and hypochlorous acid in rat
Abstract:
The problem of trihalomethane formation now exists with the use of chlorine (technically, a mixture of HOCl and OCl-, depending on pH) as a disinfectant in drinking water. Monochloramine (NH2Cl) may be considered as an alternative to HOCl as a disinfectant in public water supplies. This study was conducted to compare the kinetics of NH2(36)Cl with HO36Cl in rats. The peak plasma levels of 36Cl occurred at 8 and 2 h for NH2(36)Cl and and HO36Cl, respectively. The distribution of NH2(36)Cl and HO36Cl was highest in plasma, while the lowest activity was observed in the fat. The half-life for 36Cl absorption was 2.49 and 2.16 h, while the elimination from plasma was 38.8 and 44.1 h after oral NH2(36)Cl and HO36Cl treatment, respectively. Urinary excretion accounted for most of the 36Cl eliminated in both treatments.
More Related Videos
Related Concept Videos
03:27Mixtures of Acids
A Mixture of a Strong Acid and a Weak Acid
In a mixture of a strong acid and a weak acid, the strong acid dissociates completely and becomes a source of almost all the hydronium ions...
02:14SN2 Reaction: Kinetics
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a reaction.