Cryptogenic fibrosing alveolitis associated with peripheral neuropathy

Eight patients who presented with fibrosing alveolitis and developed peripheral neuropathy are described. Seven had a positive rheumatoid factor, but only one had arthritis. The neuropathy affected both motor and sensory fibres. Two patients underwent peripheral nerve biopsy, one showing vasculitis and the other an axonal neuropathy. The two disorders responded differently to corticosteroid therapy, and immunosuppressant drugs may be useful in treating the neuropathy. The similarities of the patients suggests that this uncommon association is a real category.