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Changes of lung water and cardiovascular parameters during neurosurgical procedures associated with various types of
Abstract:
With the Swan-Ganz catheter and double indicator technique cardiovascular parameters and lung water were measured in 16 neurosurgical procedures. Five hundred millilitres of whole blood, Manitol or Fluosol-DA, or 1000 ml of lactate-Ringer solution was infused within 30 min, and various parameters were estimated and analysed. Extravascular lung water did not change with either solutions. Fluosol-DA showed the most powerful pressure effects. With whole blood and Fluosol DA, cardiac output and oxygen availability increased. Marked hemodilution was observed with the infusion of either Manitol, Fluosol-DA or lactate-Ringer solution, but only Fluosol-DA insured adequate oxygen supply to tissues by increase in oxygen capacity in blood. Fluosol-DA proved to be one of the suitable colloidal solutions to improve the hemodynamics and hemodilution during operation.