[Effect of tiapride in acute manifestations of alcohol withdrawal]

The purpose of this trial was to evaluate the effect of tiapride in alcohol withdrawal. The same very strict protocol was applied to each of 90 hospitalized male patients. Starting from 12 intravenous vials daily, in 4 doses, dosage was slowly brought down to 3 tablets per day, in 3 doses, by the 5th day. Effectiveness of Tiapride proved excellent, as soon as the first four days, mainly on psychiatric and digestive manifestations, while it was satisfactory on pain and less so on tremor. Overall tolerance was good. Attention is drawn to the very rapid action of Tiapride, which results in a 50% decrease in the duration of the hospital stay.