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Cystosarcoma phylloides in adolescent female patients
American Journal of Surgery
|December 1, 1983
Summary
Excision is the preferred initial treatment for cystosarcoma phylloides in adolescent females, regardless of tumor type. While malignant tumors may recur, reexcision is effective, and breast-sparing surgery is recommended.
Area of Science:
- Oncology
- Surgical Pathology
- Adolescent Medicine
Background:
- Cystosarcoma phylloides is a rare breast tumor.
- Adolescent presentation requires specific management considerations.
Purpose of the Study:
- To analyze outcomes of cystosarcoma phylloides in adolescent females.
- To establish optimal initial treatment strategies for this demographic.
Main Methods:
- Retrospective review of nine institutional cases.
- Meta-analysis of 35 additional cases from existing literature.
- Analysis of lesion classification, treatment modalities, and recurrence rates.
Main Results:
- Out of 44 cases, 84.1% were benign, 13.6% malignant, and 1% borderline.
- Excision was performed in 35 patients; 9 underwent mastectomy.
- Recurrence rate was 6.8% (3/44), with wide excision successful for recurrent lesions.
Conclusions:
- Excision is the recommended initial therapy for adolescent cystosarcoma phylloides.
- Malignant lesions have a higher recurrence risk but are manageable with reexcision.
- Breast-sparing surgery is strongly advised over mastectomy for initial treatment.