Molecular size of the human platelet alpha 2-adrenergic receptor as determined by radiation inactivation

The size of the alpha 2-adrenergic receptor in human platelet membranes has been determined by radiation inactivation/target size analysis to be 160,000 daltons. The size of the platelet alpha 2-receptors is essentially identical to that of the alpha 1-adrenergic receptor of the rat liver membrane.