Histologic reaction to a new microsurgical suture in rabbit reproductive tissue

A newly introduced coated polyglactin suture was compared with a polyglycolic acid suture following microsurgical repair of standard rabbit uterine incisions. The degree of inflammatory response and tissue fibrosis for each suture was scored, and the results were compared. At 30 days, an inflammatory response was noted in both groups, with a greater response noted in the polyglycolic acid group. At 90 days, the inflammatory response and tissue fibrosis at the site of repair was evident in both groups, with no significant difference between the groups. The previously reported difference between these two absorbable suture materials in their earlier formulations could not be demonstrated in rabbit reproductive tissue. If an absorbable suture is used for tubal surgery, the choice can be made on considerations other than tissue reactivity.