Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Bi-Profenid in rheumatologic practice].

B Mazières, J M Harrewyn, J Arlet

    La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
    |December 12, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prevalence of pelvic Paget's disease of bone in France.

    Bone·2017
    Same author

    Sense of extension force and angle of the knee joint are correlated between two generations of men.

    Journal of sports sciences·2017
    Same author

    Prevalence of symptomatic hip and knee osteoarthritis: a two-phase population-based survey.

    Osteoarthritis and cartilage·2011
    Same author

    EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis.

    Annals of the rheumatic diseases·2009
    Same author

    A case-control study to assess sensitivity and specificity of a questionnaire for the detection of hip and knee osteoarthritis.

    Arthritis and rheumatism·2009
    Same author

    Screening for hip and knee osteoarthritis in the general population: predictive value of a questionnaire and prevalence estimates.

    Annals of the rheumatic diseases·2007
    Same journal

    [Dizziness, lipothymia, syncope; symptomatology and therapy].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Antral reaction; its semeiologic value in ulcers of the lesser curvature].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Electrocardiographic and anatomoclinical collation in a case of infarct Tn type].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Are there dissociated forms of hypocorticalism; biogram in chronic adrenal insufficiency].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    Paradoxical blood pressure collapse and sudden death in paroxysmal arterial hypertension linked to adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    Same journal

    Paroxysmal arterial hypertension by adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    See all related articles

    Bi-Profenid effectively reduced pain in patients with inflammatory and degenerative conditions, including arthrosis. Most patients tolerated the medication well, with gastric pain being the most frequent side effect.

    Area of Science:

    • Pharmacology and Therapeutics
    • Rheumatology
    • Pain Management

    Background:

    • Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for inflammatory and degenerative conditions.
    • Bi-Profenid (ketoprofen lysinate) is an NSAID with analgesic and anti-inflammatory properties.
    • Assessing the efficacy and tolerance of Bi-Profenid in a clinical setting is important for pain management.

    Purpose of the Study:

    • To evaluate the effectiveness of Bi-Profenid in managing pain associated with inflammatory and degenerative conditions.
    • To assess the impact of Bi-Profenid on various pain parameters, including pain upon mobilization, nocturnal pain, overall pain, and articular index.
    • To determine the overall tolerance and identify common side effects of Bi-Profenid treatment.

    Main Methods:

    Related Experiment Videos

    • A 20-day outpatient trial involving 66 patients with inflammatory or degenerative conditions.
    • Patients received Bi-Profenid at a dosage of 300 mg per day, divided into two 150 mg doses.
    • Pain assessment included pain upon mobilization, nocturnal pain, pain index, and articular index using a pain scale.

    Main Results:

    • Statistically significant improvements in pain upon mobilization, nocturnal pain, and pain index were observed in patients with degenerative diseases.
    • Significant reductions in nocturnal pain, overall pain, and improvements in the articular index were noted in patients with inflammatory conditions.
    • Over 65% of patients experienced satisfactory tolerance; gastric pain was the most common side effect (22.7%).

    Conclusions:

    • Bi-Profenid demonstrates significant efficacy in alleviating pain related to arthrosis (degenerative) and inflammatory conditions.
    • The medication provides effective pain relief across multiple pain metrics in both patient groups.
    • Bi-Profenid is generally well-tolerated, suggesting its utility as a treatment option for these conditions.