Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Repeat gestational trophoblastic disease.

P K Sand, J R Lurain, J I Brewer

    Obstetrics and Gynecology
    |February 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mycobacterium bovis infection in a grey seal pup (Halichoerus grypus).

    The Veterinary record·2013
    Same author

    Transforming growth factor beta1 gene expression during vaginal wound healing in a rabbit menopause model.

    BJOG : an international journal of obstetrics and gynaecology·2012
    Same author

    Chorionic gonadotropin in the diagnosis of testicular tumors.

    Archives of pathology·2010
    Same author

    Chorionic gonadotrophin in the diagnosis of testicular tumors.

    The Proceedings of the Institute of Medicine of Chicago·2010
    Same author

    Studies on the human corpus luteum: histologic variations in corpora lutea and in corpus luteum endometrial relationships at the onset of normal menstruation.

    American journal of obstetrics and gynecology·2010
    Same author

    Carcinoma of the cervix; surgical aspects.

    Radiology·2010

    Repeat gestational trophoblastic disease occurred in 1.33% of patients. Subsequent events increased risk, but many patients still delivered viable infants, irrespective of prior chemotherapy.

    Area of Science:

    • Gynecology
    • Oncology
    • Reproductive Medicine

    Background:

    • Gestational trophoblastic disease (GTD) is a rare pregnancy complication.
    • Understanding the recurrence patterns and outcomes of GTD is crucial for patient management.

    Purpose of the Study:

    • To determine the incidence and characteristics of recurrent gestational trophoblastic disease.
    • To evaluate the risk of subsequent GTD events and pregnancy outcomes after recurrence.

    Main Methods:

    • Retrospective analysis of 1648 patients referred to a specialized Trophoblastic Disease Center over a ten-year period (1969-1979).
    • Identification of patients with repeat GTD episodes and analysis of disease progression and outcomes.

    Main Results:

    Related Experiment Videos

  • An incidence of 1.33% for recurrent GTD was observed in 22 out of 1648 patients.
  • Invasive mole or choriocarcinoma was more common in second GTD events (32%) than first (14%).
  • Seventeen patients (77%) experienced consecutive GTD episodes, with a 28% risk after a second event, yet 44% achieved viable births.

    • Conclusions:

    • Recurrent GTD, while carrying an increased risk for subsequent events, does not preclude successful future pregnancies.
    • Chemotherapy for a previous GTD episode did not negatively impact the outcome of subsequent pregnancies.