Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Viruses and asthma].

P Scheinmann, M R Benoist, J de Blic

    La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
    |November 24, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    EMC. Pediatria·2020
    Same author

    [Acute viral respiratory tract infections and childhood asthma].

    Revue francaise d'allergologie et d'immunologie clinique·2020
    Same author

    [An unusual foreign body. Report of a case of subcutaneous emphysema during an asthma attack].

    Revue francaise d'allergologie et d'immunologie clinique·2020
    Same author

    EMC. Pediatria·2020
    Same author

    Remodelling and inflammation in preschoolers with severe recurrent wheeze and asthma outcome at school age.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2018
    Same author

    Non-immediate-reading skin tests and prolonged challenges in non-immediate hypersensitivity to beta-lactams in children.

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2017
    Same journal

    [Dizziness, lipothymia, syncope; symptomatology and therapy].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Antral reaction; its semeiologic value in ulcers of the lesser curvature].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Electrocardiographic and anatomoclinical collation in a case of infarct Tn type].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Are there dissociated forms of hypocorticalism; biogram in chronic adrenal insufficiency].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    Paradoxical blood pressure collapse and sudden death in paroxysmal arterial hypertension linked to adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    Same journal

    Paroxysmal arterial hypertension by adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    See all related articles

    Respiratory Syncytial Virus (RSV) bronchiolitis can lead to recurrent wheezing in infants. Viral infections in children with asthma trigger attacks by causing immunological and respiratory disorders.

    Area of Science:

    • Pediatric Respiratory Medicine
    • Immunology
    • Viral Pathogenesis

    Context:

    • Respiratory Syncytial Virus (RSV) infection is a common cause of bronchiolitis in infants.
    • A significant proportion of infants with RSV bronchiolitis develop recurrent wheezing.
    • Viral infections are known triggers for asthmatic attacks in children.

    Purpose:

    • To investigate the immunological and respiratory functional differences between infants with RSV bronchiolitis who wheeze and those who do not.
    • To explore the role of viral infections in triggering allergic sensitization and bronchial hyperreactivity in children.
    • To examine the factors contributing to bronchoconstriction during viral respiratory infections.

    Summary:

    • Infants with RSV bronchiolitis who experience wheezing exhibit increased T-lymphocyte responsiveness to RSV antigen, persistent IgE bound to nasopharyngeal cells, and higher RSV-specific IgE and histamine levels.

    Related Experiment Videos

  • Viral infections can induce allergic sensitization in atopic children and enhance histamine release from basophils.
  • Non-specific bronchial hyperreactivity, a hallmark of asthma, is also observed in viral respiratory infections, potentially due to airway epithelial injury and other factors.

    • Impact:

    • Findings highlight the link between RSV infection, wheezing, and potential asthma development in infants.
    • Understanding these mechanisms can inform strategies for preventing recurrent wheezing and managing viral-induced asthma exacerbations.
    • Further research is needed to determine the congenital or acquired nature of virus-induced bronchial hyperreactivity.