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Related Experiment Videos

Colorectal bleeding localized with gamma camera.

P Rosenkilde Olsen, L Nielsen, M Dyrbye

    Acta Chirurgica Scandinavica
    |January 1, 1983
    PubMed
    Summary

    This study shows that technetium-99m labeled red blood cell scintigraphy accurately locates colorectal bleeding in patients with active hemorrhage. This non-invasive imaging helps surgeons plan procedures, improving diagnostic accuracy for gastrointestinal bleeding.

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    Area of Science:

    • Nuclear Medicine
    • Gastroenterology
    • Surgical Planning

    Background:

    • Colorectal bleeding diagnosis can be challenging, often requiring invasive procedures.
    • Accurate localization of bleeding is crucial for effective surgical intervention.

    Purpose of the Study:

    • To evaluate the efficacy of in-vivo labeled erythrocyte scintigraphy using 99mTc-pertechnetate for localizing colorectal bleeding.
    • To determine if this non-invasive method can guide surgical planning for patients with lower gastrointestinal hemorrhage.

    Main Methods:

    • A prospective study involving 24 patients with colorectal bleeding.
    • In-vivo labeling of erythrocytes with 99mTc-pertechnetate followed by gamma camera imaging.
    • Scintigraphic localization compared with clinical findings and surgical outcomes.

    Main Results:

    • Correct localization of bleeding was achieved in 7 of 8 patients with bright-red rectal bleeding.
    • Scintigraphy was negative in 8 of 11 patients with recent but not acute bleeding.
    • The scintigraphic classification demonstrated significant accuracy (p < 0.02).

    Conclusions:

    • 99mTc-labeled erythrocyte scintigraphy is effective for identifying and localizing active colorectal bleeding.
    • This non-invasive technique aids in surgical planning and may precede more invasive arteriography.

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