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Virus-associated hemophagocytic syndrome due to Epstein-Barr virus
Human Pathology
|March 1, 1984
Abstract:
The clinical and autopsy findings in a case of virus-associated hemophagocytic syndrome in a previously healthy 17-year-old girl are presented. Serum titers to Epstein-Barr viral antigens were unusually elevated. In addition to widespread proliferation of hemophagocytic histiocytes and lymphoid depletion, there were areas of non-suppurative necrosis in lymph nodes and spleen, which have not been previously reported.