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[Therapy evaluation in rheumatology with an electronic data processing system].

N Thumb, H Grabner, F Gruber

    Acta Medica Austriaca
    |January 1, 1976
    PubMed
    Summary
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    A new system quantifies rheumatic disease severity using the rheuma-number and Masszahl indices. This method aids in statistically evaluating therapeutic effects for rheumatic conditions.

    Area of Science:

    • Rheumatology
    • Medical Informatics
    • Biostatistics

    Background:

    • Evaluating therapeutic effects in rheumatic diseases requires objective and statistically valid measures.
    • Standardized documentation of joint status is crucial for consistent patient assessment.
    • Existing methods may lack the precision needed for detailed statistical analysis of treatment outcomes.

    Purpose of the Study:

    • To introduce a novel system for evaluating therapeutic effects in rheumatic diseases.
    • To present two key indices, the rheuma-number and Masszahl, for quantitative assessment.
    • To demonstrate the system's utility in clinical studies.

    Main Methods:

    • Standardized physical joint examinations are recorded on specialized mark-pages.
    • Data from mark-pages are entered into a computer system via a mark-page-reader.

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  • A dedicated computer program calculates negative-points, forming the rheuma-number, and the Masszahl index.
  • Main Results:

    • The system automatically calculates the rheuma-number, reflecting joint change severity.
    • The Masszahl index, comprising measured values like range of motion, is separately provided.
    • The system's practicability was confirmed through studies on antirheumatic-corticosteroid combinations and immunosuppressives in rheumatoid arthritis patients.

    Conclusions:

    • The presented system offers a quantifiable and statistically treatable method for assessing rheumatic disease progression.
    • The rheuma-number and Masszahl provide objective data for evaluating treatment efficacy.
    • This system facilitates rigorous clinical research in rheumatology, particularly for rheumatoid arthritis.