Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Bullous pemphigoid. Current aspects].

P Bernard, A Rommel

    La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
    |January 19, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Excess costs of type 2 diabetes and their sociodemographic and clinical determinants: a cross-sectional study using data from the German Health Interview and Examination Survey for Adults (DEGS1).

    BMJ open·2021
    Same author

    [Frequency of falls among clients of home care services : The importance of care-related and social risk factors].

    Zeitschrift fur Gerontologie und Geriatrie·2017
    Same author

    [A Consensus German Reporting Standard for Secondary Data Analyses, Version 2 (STROSA-STandardisierte BerichtsROutine für SekundärdatenAnalysen)].

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2016
    Same author

    A Consensus German Reporting Standard for Secondary Data Analyses, Version 2 (STROSA-STandardisierte BerichtsROutine für SekundärdatenAnalysen).

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2016
    Same author

    [Utilization of Physiotherapy Services by Children and Adolescents - Results of the KiGGS- Baseline Survey].

    Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2016
    Same author

    [Utilization of Occupational Therapy in Children - Results from the KiGGS Basis Survey].

    Klinische Padiatrie·2016
    Same journal

    [Dizziness, lipothymia, syncope; symptomatology and therapy].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Antral reaction; its semeiologic value in ulcers of the lesser curvature].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Electrocardiographic and anatomoclinical collation in a case of infarct Tn type].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    [Are there dissociated forms of hypocorticalism; biogram in chronic adrenal insufficiency].

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2014
    Same journal

    Paradoxical blood pressure collapse and sudden death in paroxysmal arterial hypertension linked to adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    Same journal

    Paroxysmal arterial hypertension by adrenal paraganglioma.

    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris·2010
    See all related articles

    Bullous pemphigoid (BP) is identified by IgG and C3 deposits in the basal membrane zone. While systemic corticotherapy offers the best results, its exact outcome and relation to other blistering diseases remain unclear.

    Area of Science:

    • Dermatology
    • Immunology

    Context:

    • Bullous pemphigoid (BP) diagnosis is enhanced by routine cutaneous immunofluorescence, revealing characteristic linear IgG and C3 deposition in the basal membrane zone.
    • Recent immunologic and electron microscopy studies provide new insights into the dermo-epidermal separation mechanism central to BP pathogenesis.

    Purpose:

    • To review the diagnostic features, clinical variations, and current understanding of bullous pemphigoid.
    • To discuss the nosologic classification challenges of BP in relation to other autoimmune blistering diseases and to evaluate treatment outcomes.

    Summary:

    • Cutaneous immunofluorescence is key for diagnosing bullous pemphigoid (BP), showing linear IgG and C3 deposits at the dermal-epidermal junction.
    • BP presents with diverse clinical manifestations, some previously unrecognized, due to improved diagnostic techniques.

    Related Experiment Videos

  • Despite advances in understanding dermo-epidermal separation, the precise nosologic position of BP relative to herpes gestationis and cicatricial pemphigoid remains undefined.

    • Impact:

    • Standardized management protocols are needed to better ascertain the long-term prognosis of bullous pemphigoid.
    • Systemic corticotherapy remains the most effective treatment for bullous pemphigoid, despite ongoing research into its precise outcomes and disease classification.