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Epstein-Barr virus infections in pregnancy: a prospective study
We studied 4063 pregnant women during 4108 gestations for evidence of infection with Epstein-Barr virus. Forty-six (1.1%) were susceptible early in gestation, and only three showed seroconversion. Two of the infants born to these three women were normal, one had tricuspid atresia. None of the infants had IgM antibodies to EBV at birth, and their cord blood lymphocytes did not give rise spontaneously to EBV-carrying lymphoblastoid cell lines. Thus we were unable to document intrauterine infection with EBV.
We studied 4063 pregnant women during 4108 gestations for evidence of infection with Epstein-Barr virus. Forty-six (1.1%) were susceptible early in gestation, and only three showed seroconversion. Two of the infants born to these three women were normal, one had tricuspid atresia. None of the infants had IgM antibodies to EBV at birth, and their cord blood lymphocytes did not give rise spontaneously to EBV-carrying lymphoblastoid cell lines. Thus we were unable to document intrauterine infection with EBV.