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Sexually transmitted diseases and carcinogenesis.

D S Roseman, J S Ansell, W H Chapman

    The Urologic Clinics of North America
    |February 1, 1984
    PubMed
    Summary

    Sexually transmitted diseases (STDs) may contribute to urogenital cancers in men and women. Viral agents are implicated in cervical, penile, testicular, prostate, and bladder cancers, and potentially in acquired immune deficiency syndrome (AIDS).

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    Area of Science:

    • Urology
    • Oncology
    • Infectious Diseases
    • Epidemiology

    Background:

    • Sexually transmitted diseases (STDs) are a global health concern.
    • The link between infectious agents and cancer development is increasingly recognized.
    • Urogenital cancers represent a significant public health challenge.

    Purpose of the Study:

    • To discuss the role of STDs in the development of male and female urogenital cancers.
    • To review evidence linking specific viral agents to various urogenital malignancies.
    • To explore current speculations on the involvement of STDs in acquired immune deficiency syndrome (AIDS).

    Main Methods:

    • Literature review of research evidence.
    • Synthesis of etiological factors in urogenital cancers.
    • Discussion of current scientific understanding and speculation.

    Main Results:

    • Evidence supports the role of specific viral agents in the etiology of cervical, penile, testicular, prostate, and bladder cancers.
    • Certain STDs are considered risk factors for these malignancies.
    • Speculation exists regarding the role of STDs in the pathogenesis of AIDS.

    Conclusions:

    • STDs, particularly viral infections, are significant etiological factors in several urogenital cancers.
    • Further research is warranted to fully elucidate the complex interplay between STDs, urogenital cancers, and AIDS.
    • Public health strategies targeting STD prevention may reduce the burden of urogenital cancers.

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