The synthesis of S-(3-aminopropyl)thiosulfuric acid

In order to investigate the metabolism in vivo of homocystamine we needed the corresponding -SSO3H derivative and we attempted to prepare it. In this paper details are reported for the synthesis of S-(3-Aminopropyl)-thiosulfuric acid from 3-Bromopropylamine or thiosulfate. Same analytical date and chromatographic properties one also reported, which allow its identification.