Related Experiment Video
Updated: Aug 14, 2026

Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays
Published on: September 23, 2015
Rat striatal cyclic nucleotide-reactive cells and acetylcholinesterase reactive interneurons are separate populations
Abstract:
The concurrent localization of cyclic nucleotide immunofluorescent cells and acetylcholinesterase-containing neurons in the rat caudate-putamen complex has been examined. Cyclic AMP and cyclic GMP stained elements do not exhibit coincident localization with the enzymatically detectable hydrolysis of acetylcholine. These data add further support for the preferential association of the cyclic nucleotides with striatal efferent projection systems, while the large cholinergic somata are part of the interneuron population of the rat caudate-putamen complex.
More Related Videos
Related Concept Videos
Cholinergic Neurons: Neurotransmission
Cholinergic Receptors: Muscarinic
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+. Activation...
Cholinergic Receptors: Nicotinic
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
The direct-acting...
Cholinesterases: Distribution and Function
Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...

