Serotonin-receptor coupled with membrane electrogenesis in a rat glioma clone

The electrophysiological consequences of serotonin application to glial cells in culture are described. Membrane hyperpolarization due to K+ permeability-increment was induced by serotonin in rat clonal glioma (C6-BU-1) cells. Similar response was recognized in some of rat cerebral cortical glial cells. Pharmacological examinations in the C6-BU-1 glioma cells suggested a participation of serotonin-receptors sharing properties known in neuronal receptors.