Related Experiment Video
Updated: Aug 8, 2026

A Method of Nodose Ganglia Injection in Sprague-Dawley Rat
Published on: November 25, 2014
Role of the right vagal nerve trunk in antinociception
Abstract:
Activation of the cardiopulmonary reflex arc by volume expansion results in antinociception of the tail-flick response to radiant heat, and this antinociception can be attenuated by resection of the right vagal nerve trunk. Resection of the right vagal nerve trunk also attenuates foot-shock induced analgesia ( FSIA ), but this vagal influence appears to be qualitatively different from that produced by volume expansion. These findings indicate that pain perception is modulated by cardiovascular input.
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