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"Recurrent herpes zoster": an unproved entity?

N S Heskel, J M Hanifin

Journal of the American Academy of Dermatology

|March 1, 1984

Summary

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Herpes simplex virus (HSV) skin infections are often misdiagnosed as recurrent zoster. Laboratory confirmation is crucial for accurate diagnosis and appropriate antiviral therapy in zosteriform eruptions.

Area of Science:

Dermatology
Virology

Background:

Recurrent zosteriform skin eruptions are sometimes misdiagnosed as herpes zoster.
This misdiagnosis can lead to inappropriate and potentially harmful treatments, especially in immunocompromised patients or those with ophthalmitis.

Observation:

Three patients presented with zosteriform eruptions initially diagnosed as recurrent herpes zoster.
Herpes simplex virus (HSV) was subsequently cultured from the vesicles in these patients.

Findings:

Most recurrent zosteriform eruptions are likely caused by HSV, not recurrent varicella zoster (VZ).
"Recurrent zoster" has not been definitively documented.
Diagnosis of recurrent zoster should require laboratory confirmation of VZ.

Implications:

Related Experiment Videos

Accurate differentiation between HSV and VZ zosteriform eruptions is critical for timely and effective antiviral treatment.
Viral culture or immunofluorescence can definitively diagnose the etiology of zosteriform lesions.
Physicians should consider HSV in the differential diagnosis of zosteriform eruptions.