Related Experiment Video
Updated: Aug 10, 2026

Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors
Published on: June 7, 2016
Evidence that adrenaline neurons in the rostral ventrolateral medulla have a vasopressor function
Abstract:
Focal electrical or chemical stimulation in the rostral ventrolateral medulla of the rat and rabbit evoked large increases in arterial pressure when the stimulus sites were in the region containing a high density of adrenaline synthesizing neurons, but much smaller or no responses when the sites were outside this region. The adrenaline neurons were identified in the rat by an immunohistochemical procedure, and in the rabbit by a modification of the FAGLU catecholamine fluorescence method. By combining the fluorescence procedure with the method of retrograde transport of horseradish peroxidase, many of the adrenaline synthesizing neurons in the rabbit were shown to project to the spinal cord.
More Related Videos
11:08Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.
Published on: February 14, 2018
06:30Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
Published on: September 11, 2018
Related Concept Videos
Adrenergic Neurons: Neurotransmission
Synthesis: Catecholamine synthesis requires tyrosine, which is taken...
Adrenergic Receptors (Adrenoceptors): Classification
α-Adrenoceptors
α-Adrenoceptors are classified into two main subtypes: α1 and α2. The α1 adrenoceptors, which are found on postsynaptic...
Adrenergic Receptors: β Subtype
Isoprenaline > Adrenaline > Noradrenaline
Neurotransmitter binding to these receptors causes activation of adenylyl cyclase resulting in increased concentrations of cAMP and modulation of calcium ion channels within the cell. They are further classified into β1, β2, and β3 subtypes.
β1-adrenoceptors: β1-adrenoceptors have equal affinities for...
Adrenergic Agonists: Direct-Acting Agents
These agents can be classified...
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Antihypertensive Drugs: Action of β1 Blockers