Role of radiation therapy in carcinoma of the hypopharynx

In a series of 199 patients with hypopharyngeal carcinoma treated with irradiation, the primary tumor was controlled in 63 per cent, 54 per cent, 44 per cent and 14 per cent of T1-T4 lesions, respectively. The five-year actuarial survival for stages I, II, III and IV patients was 60 per cent, 66 per cent, 49 per cent and 18 per cent. It was significantly better in patients with tumors located at the upper hypopharynx (p = 0.024). Early lesions yielded satisfactory results with irradiation alone. Advanced tumors had poor prognosis and other treatment modalities along with irradiation should be tried.