[Familial hemolytic-uremic syndrome associated with Coxsackie B infection]

Authors describe hemolytic uremic syndrome (HUS) in two siblings whose onset occurred within eight days. There was evidence of having recent infection with Coxsackie B virus. Clinical course, treatment and outcome of patients are reported, showing differences on the severity of renal failure and platelet consumption. Recovery of renal function was evidenced in both infants. One of them critically thrombopenic and with oligoanuric renal failure was treated with peritoneal dialysis, aspirin and dipyridamole. Previous familial HUS reports and its' association with viral infection have been reviewed.