Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Structural homologies among type I restriction-modification systems.

N E Murray, J A Gough, B Suri

    The EMBO Journal
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The moderating role of social media motives in the relationship between screen usage and cybervictimization.

    Child abuse & neglect·2025
    Same author

    Large Collective Lamb Shift of Two Distant Superconducting Artificial Atoms.

    Physical review letters·2019
    Same author

    Decoupling a Cooper-pair box to enhance the lifetime to 0.2 ms.

    Physical review letters·2011
    Same author

    Experimental observations on the aural effects of gunblast.

    The Medical journal of Australia·2010
    Same author

    Temporary deafness due to gunfire.

    The Journal of laryngology and otology·2010
    Same author

    Hearing aids.

    Bulletin of the Post-Graduate Committee in Medicine, University of Sydney·2010
    Same journal

    PP2A phosphatase regulates Hippo signalling in dual manner.

    The EMBO journal·2026
    Same journal

    The TPR2 corepressor forms condensates with repressors to fine-tune growth and development in rice.

    The EMBO journal·2026
    Same journal

    SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program.

    The EMBO journal·2026
    Same journal

    Scalable phosphotyrosine enrichment with SH2 superbinder enables deep profiling of EGF responses.

    The EMBO journal·2026
    Same journal

    Essential nucleus-apical pole linkage maintains division fidelity during Plasmodium progeny formation.

    The EMBO journal·2026
    Same journal

    From cell atlases to mechanisms: bridging scRNA-seq discovery with in vivo genetics.

    The EMBO journal·2026
    See all related articles

    This study investigated restriction-modification systems in bacteria. Researchers found significant structural similarities between Escherichia coli K12 and Salmonella restriction enzymes, but surprisingly, no homology with the E. coli A system.

    Area of Science:

    • Molecular Biology
    • Microbiology
    • Genetics

    Background:

    • Restriction-modification systems are crucial for bacterial defense and genome maintenance.
    • Escherichia coli and Salmonella species possess diverse restriction-modification systems with varying specificities.

    Purpose of the Study:

    • To investigate structural homologies among restriction systems of Escherichia coli and Salmonella species.
    • To compare the E. coli K12 restriction-modification system with those of E. coli B and Salmonella SB, SP, and SQ using immunological and DNA hybridization methods.

    Main Methods:

    • Immunological methods utilizing antibodies against E. coli K12 restriction enzyme subunits.
    • DNA hybridization experiments employing fragments of E. coli K12 hsd genes as probes.

    Related Experiment Videos

    Main Results:

    • Strong homology was observed between the restriction-modification systems of E. coli K12 and E. coli B.
    • Marked, though weaker, homology was found between E. coli K12 and Salmonella systems SB, SP, and SQ.
    • Surprisingly, no homology was detected between the E. coli K12 and E. coli A restriction systems.

    Conclusions:

    • The findings reveal significant evolutionary relationships and structural conservation among certain bacterial restriction-modification systems.
    • The lack of homology with the E. coli A system suggests a distinct evolutionary trajectory or divergence.