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Patterns of diabetes mellitus in young Africans and Indians in Natal
Insights
This study examined diabetes mellitus patterns in young African and Indian patients. Indian patients showed a higher prevalence of non-insulin-dependent diabetes mellitus (NIDDM) and earlier onset of insulin-dependent diabetes mellitus (IDDM).
Area of Science:
- Endocrinology
- Diabetology
- Population Health
Background:
- Diabetes mellitus presents diverse etiological patterns across different ethnic groups.
- Understanding these patterns is crucial for targeted public health interventions and clinical management.
Purpose of the Study:
- To investigate and compare the patterns of diabetes mellitus in young African and Indian patients.
- To identify demographic and clinical characteristics associated with different diabetes types in these populations.
Main Methods:
- Retrospective analysis of 110 African and 101 Indian patients diagnosed with diabetes before age 35.
- Categorization based on diabetes type: Insulin-Dependent Diabetes Mellitus (IDDM) and Non-Insulin-Dependent Diabetes Mellitus (NIDDM).
- Evaluation of age of onset, seasonal variations, obesity, and family history.
Main Results:
- African patients: 86 IDDM, 18 NIDDM. Indian patients: 40 IDDM, 60 NIDDM.
- IDDM onset was earlier in Indians (mean 17 years) vs. Africans (mean 23 years).
- NIDDM showed female predominance (3:1) and obesity association; 80% of Indian and 39% of African NIDDM patients had a positive family history.
Conclusions:
- Significant differences exist in diabetes mellitus types and onset characteristics between young African and Indian populations.
- NIDDM in these groups is linked to obesity, female sex, and a strong family history, particularly in Indians.
- Tropical diabetes subtypes were infrequent in both studied groups.
Abstract:
Young African and Indian patients (age of onset under 35) were studied in order to determine the pattern of diabetes mellitus seen in these groups. Of the 110 African patients 86 had IDDM and 18 NIDDM, whereas of the 101 Indian patients the distribution was 40 and 60 respectively. Tropical diabetes (J-type and Z-type) was rare in both groups. IDDM tended to start at an earlier age in Indians (mean 17 years) compared to Africans (mean 23 years). Onset of the disease tended to be more frequent in winter, particularly in Indian patients. NIDDM was associated with a female predominance (3:1) and obesity in both population groups. A positive family history of diabetes mellitus was obtained from 80% of the Indian and 39% of the African patients with NIDDM.
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