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Published on: December 29, 2012

T cell nature of adjuvant peptide--induced antitumor cell-mediated cytotoxicity

A E Eggers, L Tarmin

    Journal of Biological Response Modifiers
    |August 1, 1984
    PubMed

    The direct cell-mediated antitumor cytotoxicity induced by coupling a murine methylcholanthrene-induced sarcoma with N-acetylmuramyl-L-alanyl-D-isoglutamine (adjuvant peptide) was eliminated by treatment of effector cells with anti-Thy 1.2 or anti-Lyt 2.2 monoclonal antibody and complement. Cytotoxicity was not H-2 restricted.

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