Cogan's syndrome: acute vestibular and auditory dysfunction with interstitial keratitis

Area of Science:

• Ophthalmology
• Neurology
• Otolaryngology

Background:

• Cogan's syndrome is a rare autoimmune disorder.
• It primarily affects the eyes and the auditory system.

Observation:

• Two patients presented with sudden bilateral hearing loss and vestibular issues.
• Slit-lamp examination revealed interstitial keratitis in both cases.

Findings:

• Both patients showed significant improvement after corticosteroid treatment.
• High-dose corticosteroids are effective in managing Cogan's syndrome.

Implications:

• Early diagnosis of Cogan's syndrome is crucial.
• Prompt corticosteroid therapy can resolve hearing loss and vestibular dysfunction.