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[Aortocoronary bypass operation in considerably reduced left-ventricular function caused by chronic ischemia]
Deutsche Medizinische Wochenschrift (1946)
|November 2, 1984
Summary
201Thallium myocardial scintigraphy can identify patients with severe ischemic heart damage who benefit from aortocoronary bypass surgery. Postoperative improvements in ejection fraction and reduced ischemia were observed in responsive patients.
Area of Science:
- Cardiology
- Nuclear Medicine
Background:
- Severe angina and reduced ejection fraction indicate significant ischemic heart disease.
- Aortocoronary bypass surgery is a revascularization strategy for such patients.
Purpose of the Study:
- To evaluate the effectiveness of 201Thallium myocardial scintigraphy in identifying patients who benefit from aortocoronary bypass surgery.
- To assess changes in left-ventricular function and myocardial ischemia before and after revascularization.
Main Methods:
- 18 patients with severe angina and ejection fraction < 46% underwent cine-angiography, echocardiography, radionuclide ventriculography, and 201Thallium myocardial scintigraphy.
- Assessments were performed pre-operatively and six months post-surgery.
Main Results:
- Nine patients (Group I) showed significant improvement in ejection fraction post-surgery (P < 0.001).
- Myocardial scintigraphy revealed a decrease in ischemic sectors from an average of 10 to 3.1 in Group I (P < 0.01).
- Patients with pre-operative ischemia in ≥7 sectors showed improved left-ventricular function.
Conclusions:
- 201Thallium myocardial scintigraphy is valuable for identifying patients with severe ischemic myocardial damage who are likely to benefit from revascularization.
- Improved ejection fraction and reduced resting ischemia correlate with successful surgical outcomes.