Isolation and purification of fetal calf serum factor promoting mouse erythrocyte rosette formation

This paper describes the isolation and purification of a dialyzable mouse erythrocyte rosette-promoting factor (MERF) contained in fetal calf serum (FCS). All rosette-promoting activity of FCS appears to be due to a low molecular weight, ribonuclease-sensitive material with biological activity promoting the expression of mouse erythrocyte receptors on a subset of human B lymphocytes.