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Related Experiment Videos

Epithelial ingrowth on an intraocular lens.

J R Samples, E M Van Buskirk

    Ophthalmic Surgery
    |October 1, 1984
    PubMed
    Summary

    Chronic uveitis and glaucoma can lead to epithelial membrane formation on intraocular lenses. Even on challenging surfaces, intraocular lenses may support epithelial cell growth.

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    Area of Science:

    • Ophthalmology
    • Cell Biology

    Background:

    • Chronic uveitis and glaucoma are significant ocular conditions.
    • Intraocular lenses (IOLs) are commonly used in cataract surgery.

    Observation:

    • An epithelial membrane was observed after 36 months in patients with chronic uveitis and glaucoma.
    • This membrane covered the retrocorneal surface, iris, and the intraocular lens.

    Findings:

    • Epithelial cells proliferated on the intraocular lens surface.
    • This growth occurred despite the intraocular lens presenting an inhospitable environment for cell adhesion and proliferation.

    Implications:

    • The findings suggest that intraocular lenses can serve as a substrate for epithelial cell growth, even in adverse ocular conditions.
    • This has potential implications for understanding and managing complications related to intraocular lenses in chronic inflammatory eye diseases.

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