Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lithium and hematopoiesis.

R D Barr, P R Galbraith

    Canadian Medical Association Journal
    |January 15, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Lithium shows potential for treating blood disorders by influencing white blood cell production. It enhances granulopoiesis, potentially aiding in conditions like neutrophilia, while also affecting red blood cell formation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evolution of adolescent and young adult oncology in Canada.

    Current oncology (Toronto, Ont.)·2019
    Same author

    Health-related quality of life in long-term survivors of acute lymphoblastic leukemia in childhood and adolescence.

    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2016
    Same author

    Accrual of adolescents and young adults with cancer to clinical trials.

    Current oncology (Toronto, Ont.)·2016
    Same author

    Nutritional status in children with cancer: Before, during and after therapy.

    Indian journal of cancer·2016
    Same author

    Measurement of socio-economic status in families of children with cancer in Guatemala.

    Pediatric blood & cancer·2014
    Same author

    A national study of the provision of oncology sperm banking services among Canadian fertility clinics.

    European journal of cancer care·2013
    Same journal

    Tularaemia; a problem in diagnosis.

    Canadian Medical Association journal·2010
    Same journal

    CONTROL of cancer.

    Canadian Medical Association journal·2010
    Same journal

    Bilateral diphtheritic external otitis treated with sulfathiazole.

    Canadian Medical Association journal·2010
    Same journal

    Hypoplastic anaemia treated with transfusions and folic acid fraction.

    Canadian Medical Association journal·2010
    Same journal

    Lauron in rheumatoid arthritis; a further report.

    Canadian Medical Association journal·2010
    Same journal

    HOW the socialist looks at national health service in England.

    Canadian Medical Association journal·2010
    See all related articles

    Area of Science:

    • Hematology
    • Pharmacology
    • Cell Biology

    Background:

    • Lithium's impact on blood cell formation is being investigated for therapeutic potential.
    • Observed effects suggest lithium influences key hematologic processes.

    Purpose of the Study:

    • To explore lithium's role in hematopoiesis, specifically granulopoiesis and erythropoiesis.
    • To understand the mechanisms by which lithium affects blood cell production.

    Main Methods:

    • Review of existing studies on lithium's effects on blood cell formation.
    • Analysis of lithium's impact on granulopoiesis and erythropoiesis at various concentrations.

    Main Results:

    • Lithium enhances granulopoiesis, leading to increased neutrophils (neutrophilia).

    Related Experiment Videos

  • Two potential mechanisms include direct stem cell action or suppression of inhibitory lymphocytes.
  • Lithium also demonstrates an inhibitory effect on erythropoiesis.

    • Conclusions:

    • Lithium's modulation of hematopoiesis suggests therapeutic value for hematologic disorders.
    • Further research is needed to clarify lithium's precise role in normal cell metabolism and disease treatment.