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Related Experiment Videos

Syphilis and pelvic inflammatory disease.

R J Rothstein, G L Sternbach, P Rosen

    JACEP
    |March 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Patients with pelvic inflammatory disease (PID) show a higher risk for syphilis. Screening this group is recommended, as 11.4% tested positive compared to 4% in controls.

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    Expression of Adhesion Molecules on the Surface of Activated Platelets is Diminished by PGI(2)-analogues and an NO (EDRF)-Donor: A Comparison Between Platelets of Healthy and Diabetic Subjects.

    Platelets·2010

    Area of Science:

    • Infectious Diseases
    • Public Health
    • Gynecology

    Background:

    • Screening all emergency department patients for venereal diseases is often impractical.
    • Pelvic inflammatory disease (PID) may indicate a higher risk for other sexually transmitted infections.
    • Identifying high-risk patient groups is crucial for efficient disease screening.

    Purpose of the Study:

    • To determine if patients clinically diagnosed with PID are at increased risk for syphilis.
    • To evaluate the utility of syphilis screening in emergency department patients with PID.

    Main Methods:

    • A study was conducted on seventy women clinically diagnosed with PID in an adult emergency department.
    • Syphilis screening was performed using three serologic tests: Venereal Disease Research Laboratory (VDRL), fluorescent treponemal antibody absorption (FTA-Abs), and treponema pallidum hemagglutination (TPHA).

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  • Results were compared to a control group of 100 individuals.

    • Main Results:

    • The incidence of positive syphilis serologies in the PID group was significantly higher (11.4%) compared to the control group (4%).
    • This suggests a strong association between a PID diagnosis and the presence of syphilis.
    • Specific tests like FTA-Abs and TPHA, alongside VDRL, proved effective in detecting syphilis in this cohort.

    Conclusions:

    • Patients with a clinical diagnosis of PID represent a high-risk group for syphilis.
    • Routine syphilis screening, utilizing FTA-Abs, TPHA, and VDRL tests, is recommended for all patients diagnosed with PID.
    • Targeted screening can improve early detection and management of syphilis in at-risk populations.