Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Barrett's esophagus: a review.

R W Sjogren, L F Johnson

    The American Journal of Medicine
    |February 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Barrett's esophagus, a complication of acid reflux, involves changes in the esophageal lining. Diagnosis requires biopsy, and while treatment aims to stop reflux, the risk of cancer persists.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Impact of HIV and hospitalization on the incidence of subsequent rifampicin-resistant tuberculosis after initiation of first-line tuberculosis treatment: a retrospective cohort study in South Africa.

    EClinicalMedicine·2025
    Same author

    The next generation: Pregnancy in adolescents and women living with perinatally acquired HIV in South Africa.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2021
    Same author

    Uptake and acceptability of medical male circumcision among young males in two culturally distinct settings in South Africa: A longitudinal, community-based study (the MACHO study).

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2020
    Same author

    Age bias in survey sampling and implications for estimating HIV prevalence in men who have sex with men: insights from mathematical modelling.

    Epidemiology and infection·2018
    Same author

    The role of immunity in the epidemiology of gonorrhoea, chlamydial infection and trichomoniasis: insights from a mathematical model.

    Epidemiology and infection·2011
    Same author

    Chemotherapy in diseases of ear, nose and throat.

    The Medical clinics of North America·2010

    Area of Science:

    • Gastroenterology
    • Oncology
    • Gastrointestinal Pathology

    Background:

    • Barrett's esophagus is a condition where the distal esophagus is lined by columnar epithelium.
    • It is a recognized complication of gastroesophageal reflux disease (GERD).
    • The exact factors causing its development in GERD patients are not fully understood, but may involve congenital elements.

    Purpose of the Study:

    • To define Barrett's esophagus and its clinical significance.
    • To outline diagnostic methods and management strategies.
    • To highlight the malignant potential of Barrett's esophagus.

    Main Methods:

    • Diagnosis is suspected via barium meal, endoscopy, or isotope scanning.
    • Endoscopic iodine staining or manometrically guided biopsy aids localization.

    Related Experiment Videos

  • Biopsy confirmation of columnar epithelium is definitive.

    • Main Results:

    • Symptoms, when present, are due to reflux complications like esophagitis, stricture, ulcer, or bleeding.
    • Barrett's esophagus carries a predisposition to malignancy.
    • Periodic endoscopic surveillance with biopsy and cytology is indicated post-diagnosis.

    Conclusions:

    • Treatment focuses on achieving objective cessation of gastroesophageal reflux.
    • Antireflux surgery may improve symptoms but doesn't eliminate the columnar epithelium or its malignant potential.
    • The impact of effective antireflux treatment on adenocarcinoma incidence remains unknown.